Welcome to the Dynein homepage, hosted in the Faculty of Biological Sciences at the University of Leeds.

 

Recent Publications

Coordinated Ciliary Beating Requires Odf2-Mediated Polarization of Basal Bodies via Basal Feet.

Koshi Kunimoto, Yuji Yamazaki, Tomoki Nishida, Kyosuke Shinohara, Hiroaki Ishikawa, Toshiaki Hasegawa, Takeshi Okanoue, Hiroshi Hamada, Tetsuo Noda, Atsushi Tamura, Shoichiro Tsukita, Sachiko Tsukita. (2012)

Cell. 148 (1-2): 189-200. Link

 

Dynein achieves processive motion using both stochastic and coordinated stepping.

Qiu W, Derr ND, Goodman BS, Villa E, Wu D, Shih W, Reck-Peterson SL. (2012)

Nat Struct Mol Biol. 2012 Jan 8. [Epub ahead of print] Link

 

Cytoplasmic Dynein Moves Through Uncoordinated Stepping of the AAA+ Ring Domains.

Dewitt MA, Chang AY, Combs PA, Yildiz A. (2011)

Science. 355(6065):221-225. Link

Mechanical stochastic tug-of-war models cannot explain bidirectional lipid-droplet transport.

Kunwar A, Tripathy SK, Xu J, Mattson MK, Anand P, Sigua R, Vershinin M, McKenney RJ, Yu CC, Mogilner A, Gross SP. (2011)

Proc Natl Acad Sci U S A. 108(47):18960-18965. Link

 

Three-dimensional structure of the radial spokes reveals heterogeneity and interactions with dyneins in Chlamydomonas flagella.

Barber CF, Heuser T, Carbajal-Gonzalez BI, Botchkarev VV Jr, Nicastro D. (2011)

Mol Biol Cell. 23(1):111-120. Link

 

Cryoelectron tomography of radial spokes in cilia and flagella.

Pigino G, Bui KH, Maheshwari A, Lupetti P, Diener D, Ishikawa T. (2011)

J Cell Biol. 195(4):673-687. Link

High-resolution imaging reveals indirect coordination of opposite motors and a role for LIS1 in high-load axonal transport.

Yi JY, Ori-McKenney KM, McKenney RJ, Vershinin M, Gross SP, Vallee RB. (2011)

J Cell Biol. 195(2):193-201. Link

 

The mechanism of dynein motility: Insight from crystal structures of the motor domain.

Cho C, Vale RD. (2011)

Biochim Biophys Acta. 1823 (1):182-191. Link

 

A unified taxonomy for ciliary dyneins.

Hom EF, Witman GB, Harris EH, Dutcher SK, Kamiya R, Mitchell DR, Pazour GJ, Porter ME, Sale WS, Wirschell M, Yagi T, King SM. (2011)

Cytoskeleton (Hoboken). 68(10):555-565. Link

 

X-ray structure of a functional full-length dynein motor domain.

Kon T, Sutoh K, Kurisu G. (2011)
Nat Struct Mol Biol. 18(6):638-642. Link

 

Neuromuscular Junction Defects in Mice with Mutation of dynein heavy chain 1.

Courchesne SL, Pazyra-Murphy MF, Lee DJ, Segal RA. (2011)

PLoS One. 6(2):e16753. Link

 

Stable Kinesin and Dynein assemblies drive the axonal transport of Mammalian prion protein vesicles

Encalada SE, Szpankowski L, Xia CH, Goldstein LS. (2011)

Cell. 144:551-565. Link

 

Crystal Structure of the Dynein Motor Domain

Carter AP, Cho C, Jin L, and Vale RD. (2011)

Science 331(6021):1159-1165.Link

 

A cytoplasmic dynein tail mutation impairs motor processivity.

Ori-McKenney KM, Xu J, Gross SP, Vallee RB. (2010)
Nat Cell Biol. 12(12):1228-1234 Link

 

Dynein at odd angles?

Hendricks AG, Lazarus JE, Holzbaur EL. (2010)
Nat Cell Biol. 12(12):1126-1128. Link